The SEMA4C Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to SEMA4C. This antibody recognizes Human antigen. The SEMA4C Antibody has been validated for the following applications: ELISA, and Western Blot.
Description
Function: Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
Subunit Structure: Interacts (via the PDZ-binding motif) with GIPC (via the PDZ domain) (By similarity). Interacts with NCDN (By similarity). Interacts (via the PDZ-binding motif) with DLG4. Interacts with PLXNB2 (By similarity).
Similarity: Belongs to the semaphorin family